Researchers Use AI Methods to 'Redefine' Alzheimer's Disease

by News-Medical

News-Medical (10/14/20) Henderson, Emily

Researchers at the University of Pennsylvania's Perelman School of Medicine are working with 11 research centers using a $17.8 million grant from the U.S. National Institute on Aging to find more precise diagnostic biomarkers and drug targets for Alzheimer's disease. They will use advanced artificial intelligence (AI) techniques to combine and pinpoint patterns in genetic, imaging, and clinical data from more than 60,000 Alzheimer's patients. The project's first goal will be to find a connection between genes, imaging, and clinical symptoms to identify the patterns anticipating Alzheimer's diagnosis and progression and to differentiate subtypes of the disease. The researchers will apply those findings to a predictive model of cognitive decline and disease progression, which can be used to guide treatment for future patients.

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